Overview

The goal of our research programme is to understand how plants respond to stresses caused by biotic and abiotic factors. We study how plants recognize pathogens and sense adverse environmental conditions, how these signals are transduced and which physiological and biochemical responses to stress are triggered. We also investigate the biological cycle of relevant pathogens and the genes that control their virulence. 

The teams in our programme work on different crops (rice, melon, solanaceous plants, etc.), as well as on the model plant Arabidopsis thaliana studying their interaction with important plant pathogens, including viruses, bacteria, fungi and oomycetes. We study antimicrobial peptide production, transcriptional and post-transcriptional regulation of plant defence responses, and cell death in disease resistance. Our research also aims at understanding the interactions between defence and development and plant responses to combined stresses. 

In collaboration with agro-biotech companies, we also devote our efforts to apply the acquired knowledge to obtain crops with enhanced resistance to pathogens and better adapted to changing environmental conditions.

Publications

Shaikh M.A.; Ramírez-Gonzales L.; Franco-Zorrilla J.M.; Steiner E.; Oortwijn M.; Bachem C.W.B.; Prat S.

StCDF1: A ‘jack of all trades’ clock output with a central role in regulating potato nitrate reduction activity (2025) New Phytologist, vol. 245 (1), pp. 282 -298 (DOI:10.1111/nph.20186)

Silvestri A.; Ledford W.C.; Fiorilli V.; Votta C.; Scerna A.; Tucconi J.; Mocchetti A.; Grasso G.; Balestrini R.; Jin H.; Rubio-Somoza I.; Lanfranco L.

A fungal sRNA silences a host plant transcription factor to promote arbuscular mycorrhizal symbiosis (2024) New Phytologist, (Article in press), (DOI:10.1111/nph.20273)

Ledford W.C.; Silvestri A.; Fiorilli V.; Roth R.; Rubio-Somoza I.; Lanfranco L.

A journey into the world of small RNAs in the arbuscular mycorrhizal symbiosis (2024) New Phytologist, vol. 242 (4), pp. 1534 -1544 (DOI:10.1111/nph.19394)

Shi B.; Felipo-Benavent A.; Cerutti G.; Galvan-Ampudia C.; Jilli L.; Brunoud G.; Mutterer J.; Vallet E.; Sakvarelidze-Achard L.; Davière J.-M.; Navarro-Galiano A.; Walia A.; Lazary S.; Legrand J.; Weinstain R.; Jones A.M.; Prat S.; Achard P.; Vernoux T.

A quantitative gibberellin signaling biosensor reveals a role for gibberellins in internode specification at the shoot apical meristem (2024) Nature Communications, vol. 15 (1), Art. number 3895 (DOI:10.1038/s41467-024-48116-4)

Silvestri A.; Bansal C.; Rubio-Somoza I.

After silencing suppression: miRNA targets strike back (2024) Trends in Plant Science, vol. 29 (11), pp. 1266 -1276 (DOI:10.1016/j.tplants.2024.05.001)