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Alex Clop

Researchers
:
Alex Clop
CSIC Researcher
Research Program: Research Group:
Institution:
CSIC

Office Tel. +34 935636600 ext 3353
Campus UAB - Edifici CRAG | 08193 Cerdanyola | BARCELONA

email:
alex.clop [at] cragenomica.es

Professional Experience

Biography:

Alex Clop is a researcher at the CRAG’s Research Program on Plant and Animal Genomics since September 2012.

Previously, he worked at King’s College London (UK; 2008-2012), Genesis Faraday Partnership (Roslin, Scotland; 2006-2008) and University of Liege (Belgium; 2003-2006) and did his PhD at the Department of Animal Sciences at the Autonomous University of Barcelona (2001).


Research Interests:

Alex’s research seeks to collect genomic information to help understanding the molecular basis of multiple phenotypes in domestic animals and humans. He uses cutting-edge approaches and technologies to study genetic variation, gene expression and epigenetic mechanisms associated to phenotypic changes.


Selected Publications:

• Clop A, Bertoni A, Spain SL, Simpson MA, Pullabhatla V, Tonda R, Hundhausen C, Di Meglio P, De Jong P, Hayday AC, Nestle FO, Barker JN, Bell RJ, Capon F, Trembath RC.

An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element.

PLoS One. 2013; 8(8):e71690.

• Knight J, Spain SL, Capon F, Hayday A, Nestle FO, Clop A; Wellcome Trust Case Control Consortium; Genetic Analysis of Psoriasis Consortium; I-chip for Psoriasis Consortium, Barker JN, Weale ME, Trembath RC.

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis.

Hum Mol Genet. 2012; 21(23):5185-92.

• Hundhausen C, Bertoni A, Mak RK, Botti E, Di Meglio P, Clop A, Laggner U, Chimenti S, Hayday AC, Barker JN, Trembath RC, Capon F, Nestle FO.

Allele-specific cytokine responses at the HLA-C locus: implications for psoriasis.

J Invest Dermatol. 2012; 132(3 Pt 1):635-41.

• Zidi A, Amills M, Tomás A, Vidal O, Ramírez O, Carrizosa J, Urrutia B, Serradilla JM, Clop A.

Short communication: genetic variability in the predicted microRNA target sites of caprine casein genes.

J Dairy Sci. 2010; 93(4):1749-53.

• Clop A, Marcq F, Takeda H, Pirottin D, Tordoir X, Bibé B, Bouix J, Caiment F, Elsen JM, Eychenne F, Larzul C, Laville E, Meish F, Milenkovic D, Tobin J, Charlier C, Georges M.

A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep.

Nat Genet. 2006; 38(7):813-8.